Guggulu (Commiphora mukul) is about mt heighted plant of Burceraceae family. The plant grows wild in the arid, rocky tracts, also in low rainy and hot. Guggulu is an oleo-gum resin which exudes out as a result of injury from the bark of Commiphora wightii (Arnott) Bhandari [syn. Commiphora mukul (Hook. Also listed as: Commiphora mukul, Commifora mukul, Guggulipid Guggul is the common name for the mukul myrrh tree, Commiphora mukul (also known as.

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Gum guggul Commiphora muul —the success story of an ancient insight leading to a modern discovery. In another study, highly significant reduction in levels of mean serum cholesterol and triglyceride was observed in groups of animals receiving high-fat diet for one month along with guggulu, which clearly demonstrated its hypolipidemic activity. Published online Oct To get email Alert]. Like all oleo resins, it causes increase in number of leucocytes and stimulates phagocytosis.

The patients with oily faces responded better to the gugulipid treatment [ 63 ].

Effects of Commiphora mukul guggulu in experimentally induced hyperlipemia and atherosclerosis. The steroidal constituents have been related with hypolipidemic and anti-inflammatory activities of the drug [ 13 ].

Journal of the American Medical Association.

Guggul also refers to the substance that the tree produces. Dr Sheetal L Thosar 1 Muku. Use cautiously in people taking red yeast rice, green tea extract, or usnic acid.

American Journal of Health-System Pharmacy. Support Center Support Center. This fraction also showed moderate scavenging effect against 2,2-diphenylpicryl hydrazyl DPPH radicals [ 60 ]. The hypolipidemic natural product Commiphora mukul and its component guggulsterone inhibit oxidative modification of LDL. It will help in treating Leprosy.


Commiphora wightii Conservation status. One of the main recommendations was the use of Guggul. Avoid use if you are taking any heart medicine. Evidence is lacking to support the use of guggul alone for the management of rheumatoid arthritis.

The lipid lowering effect of guggulu with special reference to atherosclerosis and commiphorz medoraga was first reported in a doctorate thesis submitted to the Banaras Hindu University BHU in January co,miphora Anti-inflammatory studies on a crystalline steroid isolated from Commiphora mukul. Safety and effectiveness have not always been proven. Bioorganic and Medicinal Chemistry. Numerous other agents may theoretically increase the risk of bleeding, although this has not been proven in most cases.

No difference was observed between the effectiveness of the steroid mixture and the purified guggulsterone E or Z.

In vitro assessments of antibacterial potential of Commiphora wightii Arn.

To get message Alert]. Myocardial necrosis induced by isoproterenol in rats jukul marked increase in serum creatine phosphokinase and glutamate pyruvate transaminase. This finding has therapeutic value in myocardial infarction and thromboembolism [ 45 ].

In other projects Wikimedia Commons Wikispecies. This plant contains a number of bioactive constituents including terpenoids, steroids, flavonoids, guggultetrols, lignans, sugars, and amino acids.

Commiphora mukul (Guggul)

Skin Diseases Administration of gugulipid was reported to be effective in the treatment of nodulocystic acne. Effect on Platelet Aggregation and Fibrinolytic Activity The purified steroid mixture from guggulu completely inhibited ADP, adrenaline, or serotonin induced platelet aggregation. Commiphora mukul, Commifora mukul, Guggulipid.

National Center for Biotechnology InformationU. Send Link Please send this muukul to: Panda S, Kar A. It prefers arid to semi arid climate.

Chemistry of ayurvedic crude drugs—IV: Monocyclic diterpenes from Commihora gugul resin Commiphora mukul Archiv der Pharmazie. Journal of Pharmacognosy and Phytotherapy. Thus the combination of antioxidant and lipid-lowering properties of guggulu makes it especially beneficial against atherogenesis [ 58 ]. It is marketed for treating parasite infections. As a result, the levels of these drugs may be altered in the blood, and may cause altered effects or potentially serious adverse reactions.


Guggulu has been used to treat obesity, osteoarthritis, rheumatoid arthritis, gout, facial paralysis, sciatica, constipation, haemorrhoids, liver disorders, inflammation, cyst, cervical lymphadenitis, coronary thrombosis, anaemia, diabetes, urinary calculus, increased frequency and turbidity of urine, and skin diseases [ 3132 ]. Use cautiously in people taking cholesterol-lowering agents.

Pharmacology and Phytochemistry of Oleo-Gum Resin of Commiphora wightii (Guggulu)

Taste of Commiphora Mukul. India’s National Medicinal Plants Board launched a project in Kutch District to cultivate to hectares 1, to 2, acres of guggal, [10] while a grass-roots conservation movement, led by IUCN associate Vineet Sonihas been started to educate guggal growers and harvesters in safe, sustainable harvesting methods.

One of the main recommendations was the use of Guggul Commiphora Mukul Dry USES Several research trials followed the discovery, culminating in studies examining Guggul’s effectiveness in humans. I am fogetting things sometime I am not able to recall names of known person also. Initial studies reported that crude guggulu has encouraging hypolipidemic activity in rabbits [ 38 ].

The gum can be purchased in a loosely packed form called dhoopan incense from Indiawhich is burned over hot coals.