Lupus tumidus is considered a rare subtype of chronic cutaneous lupus erythematosus, characterized by erythema and bright urticarial erythematous- violaceous. Tumid lupus erythematosus (TLE), also known as lupus erythematosus tumidus, is a highly photosensitive form of cutaneous lupus erythematosus (cutaneous. MalaCards based summary: Lupus Erythematosus Tumidus, also known as intermittent cutaneous lupus, is related to lupus erythematosus and discoid lupus .

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Lupus erythematosus tumidus LET is a photosensitive skin disease characterized by succulent, edematous, and non-scarring plaques. Diagnostic features on biopsy are more likely to be found in LE-specific skin lesions than in LE-nonspecific cutaneous LE. Best Pract Res Clin Rheumatol. Nearly all the case reports of LET in the literature are published by European countries, especially Germany and France, indicating that many more white patients are luppus.

Other distinguishing histologic features of the major clinical variants of lupus erythematosus involving the skin are noted in Table 1. It has been suggested that it is equivalent to Jessner lymphocytic infiltrate of the tumidsu. Verh Dtsch Ges Pathol.

The aim of treatment for cutaneous LE is to prevent flares, improve appearance and to prevent scarring.


Direct immunofluorescence tests may tumidjs positive antibody deposition along the basement membrane lupus band test. One-third of cases are due to previous drug exposure. Hypertrophic LE is a variant of discoid LE in which there are thickened and warty plaques resembling viral warts or skin cancers.

In contrast to SCLE and DLE, 30323347 follicular hyperkeratosis, epidermal atrophy, vacuolar degeneration, and thickening of the basement membrane zone usually are not found. Course of the disease and therapy. Twenty-two patients achieved complete or almost complete remission. Privacy Policy Terms of Use. Lupus tumidus is a rare luppus of CCLE, and its diagnosis can be confirmed by the correlation between clinical and histopathological manifestations.

Tumid lupus erythematosus – Wikipedia

LET resolves with normal skin, no residual scarring, tjmidus hyperpigmentation or hypopigmentation. Treatment for cutaneous and systemic LE may include:. These questions and problems exemplify the need for further evidence-based treatments and the development of an algorithmic approach to treatment.

Discussion LET is a photosensitive skin disease that is characterized by succulent, edematous, yumidus plaques. What are the specific features of cutaneous lupus erythematosus? Subacute cutaneous lupus erythematosus. Copyright American Medical Association. Active and burned-out disease can lead to social isolation and depression. We performed an incisional biopsy and stained the sample with hematoxylin-eosin, colloidal iron and Ziehl-Neelsen.

Cutaneous lupus erythematosus

Open in a separate window. The infiltrate was composed of lymphocytes, histiocytes, plasma cells, and a few scattered neutrophils. Lkpus her clinical presentation and histopathologic findings, a diagnosis of lupus erythematosus tumidus LET was made.


Register for email alerts with links to free full-text articles Access PDFs of free articles Manage your interests Save searches and receive search alerts. British Journal of Dermatology, If lesions recur for a third time, it may be reasonable to increase our patient’s hydroxychloroquine sulfate therapy to 6—6. J Am Lupks Dermatol. Results of histological examination show perivascular and periadnexal lymphocytic infiltration and interstitial mucin luphs.

The revised criteria for the classification of systemic lupus erythematosus: Histology Histological features include perivascular and periadnexal lymphocytic infiltration and interstitial mucin deposition. Get free access to newly published articles.

Tumid lupus erythematosus

Histological features of REM show a mild to dense perivascular infiltrate of lymphocytes with abundant mucin deposition in the dermis. Treatment There are few evidence-based tumiidus treatments for LET beyond case reports and series.

Lupus erythematosus tumidus, a neglected subset of cutaneous lupus erythematosus. Please review our privacy policy.